Ive written quite a bit about BHRT (which I am on and have been on for more than 10 years now) you can read many these articles on Smart Publications website. AlgaeCal Plus is giving you 350 mg, an amount that perfectly balances the 720 mg of calcium it provides. Consequently, they have a very large interface with extracellular fluids, and numerous interactions between ions from the extracellular fluid and ions constituting apatite crystals are thus possible. PMID: 22902986, Cornish J, Naot D. Lactoferrin as an effector molecule in the skeleton. I also found interesting the researchers comment that iodine insufficiency might have been a contributing factor. Hi Lara, I understand that Strontium Citrate do not cause blood clot. As you can see from the references listed below, in the Niu et al. Meat from free range, pastured animals should be good for you when consumed in small amounts along with plenty of vegetables. I too have the same concern about the replacement of bone with strontium vrs calcium. I read in the discussion that a GFR of 50 or less would indicate that I should not take Strontium. They ALL returned to the exercise program and completed a modified regimen without problems. Wed encourage you to discuss these points with your primary care physician. The women in the exercise group were asked to attend hour-long training sessions, supervised by a qualified physiotherapist, for a 6-month period each year (this was a 30-month study) and were also asked to train 20 min daily at home following a program of similar exercises to those in the supervised sessions. A few, marked low sodium, will be low in salt, but they are also going to be low in all the good things you need to build bones! Did the results convince you that this regimen is beneficial? At all the applied doses, incorporation of strontium produced no significant change in the crystal lattice parameters, even if the ionic radius of Sr21 (1.13 ) is slightly larger than that of Ca21 (0.99 ) (Table 1). Strontium ranelate slows down the cells that break down bone. Hello! . Cortical bone also accumulates far more slowly. PHD, MBA - Head of Research & Development Center of Bone Diseases, Lausanne University Hospital CHUV, Switzerland. My husband, Dr. Joe Pizzorno, is approaching age 70 and still playing basketball with men half his age; I had him read my review and he has started taking strontium at a half dose as well to protect his knees as I also showed him some good studies showing strontium helps maintain healthy cartilage in the joints. How much vitamin D3 (I hope she takes D3 as it is significantly more effective for us than D2) is she taking? It would be very helpful if you could send me the lab data specifics here 1.03 what? You want to do exercises that strengthen the muscles running up your back along both sides of your spine these are called the multifidi and erector spinae. Monitoring bone strontium levels of an osteoporotic subject due to self-administration of strontium citrate with a novel diagnostic tool, in vivo XRF: a case study. Hello Cinzia, DXA only checks BMD, which is a measure of quantity. You were correct. If this does not help, you should see your doctor to rule out other causes of gastritis (stomach inflammation), such as H. pylori infection or problems with your gallbladder or pancreas both of which are involved in digestion (the gallbladder secretes bile, pancreas produces pancreatic enzymes), so their dysfunction can cause nausea. I have read your posts to know you are much more aggressive than this. Here s a link to Dr. Grouts website: http://www.arizonaadvancedmedicine.com Or you could have become sensitive to some component in your food. Are you familiar with this brand? When I stop taking it the headaches stop. Hope that helps and that you feel better soon! Is your inflammation under control now that you have eliminated dairy and nightshade vegetables from your diet? No need to take strontium on an empty stomach. Ive been getting abdominal discomfort, bloating and cramping. Only beneficial effects for strontium citrate. Both have been shown in the research to significantly lessen risk of falling (and thus of fractures). If I do continue on it, will this contribute to a worsening of my existing kidney disease? Most medical authorities in the field of vitamin D research, e.g., Dr Michael Holick, also check the Vitamin D Council, recommend at least 2,000 IU/day. Kind regards I have read some articles about using a lower dose of strontium. Im asking because the mineral strontium does not cause these effects, but the citrate provided by Strontium Boost, which is strontium citrate, can if some unfriendly bacteria are present in your digestive tract. Hi Lara. So to me you are like an angel. The use of strontium ranelate has never been approved in the U.S. and is now significantly restricted in Europe, while strontium citrate is freely available. Would you have access to a means of contacting Li through the HKU Scholars Hub? However, you must take Strontium either without food or if with a meal, it should be a meal that does not contain calcium. 2017 Feb;105(2):433-442. doi: 10.1002/jbm.a.35917. The apatite crystals that contain strontium ions are more stable, have more regular shapes and are more resistant to stress. It is extremely effective truly close to miraculous in its healing effects. Please let me know what you suggest in order to take the AlgaeCal Plus to ingest a healthy amount of calcium. 350, 459-468. http://pstvet.com/pst/clinicalnew.htm and http://pst-global.com/images/1-22.pdf. I have seen nothing in the recent research to indicate competition for absorption between strontium and iron or magnesium. One capsule gives us 118 mg of strontium and 220 mg of citrate. The drug makes your bones stronger and lowers your chances of getting fractures. And its what I do for myself. Although you only need 3 milligrams of boron daily, this is a trace mineral that is difficult to get even in that small amount from the diet. Hi David, thanks for your questions! Thanks, delighted you have found the blogs and Your Bones helpful. Hello Lara, I have learned a great deal about strontium citrate and the other bone supplements reading the answers to the questions posted. Great article, it clears up my concern for safety and Strontium! Below, Ive copied in for you two abstracts of recent papers discussing this. These are really great questions, and I am so sorry to hear of what you are going through. Strontium citrate is also very safe, again, no adverse effects have been seen with natural forms of strontium (ie strontium citrate) if more calcium is being consumed than strontium. And increased bone density is closely correlated with lowered risk of breaking a bone. Re your question above, best outcome would be if very little of either the strontium or the citrate were excreted. For example, if your diet is giving you 400 mg of calcium each day, then you need to take 800 mg of calcium in the form of a supplement. I hope this will fully clear up your confusion, and now that AlgaeCal is aware of the potential for misunderstanding, steps can be taken to make the label on Strontium Boost easier to understand correctly. Plus, it is well-known that our consumption of plant foods is far below recommended amounts so it is unlikely you are getting sufficient strontium in your diet. Hi Lara: I can only have a bone density test done every two to three years. Hi Lara, you have mentioned your improved BMD DEXA results after taking Algaecal products including strontium. I eat the calcium-dense foods (e.g., yogurt, goat cheese, cottage cheese, soymilk enriched with calcium, tofu, spinach) at breakfast and dinner. Strontium ranelate improves bone resistance by increasing bone mass and improving architecture in intact female rats. The range that it should be was given as less than 61. The other study cited (Korpelainen et al.) I was taking Fasomac for three years with the doctors advice. Of course, happy to do what I can to be of help, and yes, each of us is our own best advocate, although you are definitely in good hands if you are working with a fully IFM certified functional medicine physician and nutritionist. Strontium Ranelate has a long list of adverse side-effects, starting with common ones like: And less common, but possibly deadly effects like: Overall, the likelihood that you will be among the ones affected may be small although a review of the research on strontium ranelate published in 2005 states Strontium [ranelate] caused a 50% increase in the risk of venous thromboembolism (including pulmonary embolism).. 1,000 micrograms is far below the 680 milligrams (which is the equivalnt of 680,000 micrograms!) Plus I am getting MK-7 in my multiple as well. Stay well, Lara. I am now taking Algaecal for about a month. Given your allergies, my best recommendation for you is to work with a knowledgeable physician who can run the tests needed to monitor precisely what is happening in YOUR body. If this happens on an empty stomach with no food present to disperse the highly concentrated vitamins and minerals, the result can be nausea. Patients were randomized to receive placebo, 0.5 g, 1 g, or 2 g SR/d for 2 yr. (2004). Replenish all the nutrients your bones start losing after age 40 and then some. I appreciate your knowledge and insight into womens bone health. I am happy to suggest some choices of natural strontium supplements for you. It has not. When referring to the SOTI and TROPOS trials, you used the term strontium but didnt specify ranelate or citrate, unless I just totally missed it. As a medical editor/writer, I typically spend 3-4 hours every day scanning the research and bone health is my special interest, so thats how I learned about AlgaeCal. How does it compare to the AlgaeCal that you recommend? I also came across Dr. Don Colberts article which also said that 170 mg is more effective and he cited Meunier (same reference that Li gave) for the information. Thank you! Unlike other meals, we almost always eat breakfast on a completely empty stomach. Trabecular bone is the soft, spongy, more metabolically-active inner portion of our bones. (Ill explain more in detail on how they differ shortly.). (Here is the reference for this study: Ma B, Zhang Q, Wang G, et al. One very important factor to consider is vitamin A. Vitamin A is the key nutrient required for immune tolerance (vitamin A is involved in causing the immune system to produce regulatory T cells of the IL-10 strain, which help tune down and resolve inflammation), and many of us are not getting adequate vitamin A, which also works in partnership with vitamin D and should be consumed in comparable amounts for the optimal benefits derived from both nutrients. So, I have finally read the paper but I found no mention of a 170 mg dose of strontium being used. Since your supplement is giving you 750 mg of strontium in 3 capsules, it looks like you are taking a different strontium citrate supplement. This has caused me to seriously wonder if Im trading one problem for a more serious one down the road. I will do my best to help you. Please take a look at my post titled Commonly Prescribed Drugs Cause Bone Loss and check any drugs you regularly take to see if they have this adverse side effect (https://blog.algaecal.com/prescription-drugs-that-cause-osteoporosis/). Thanks again for your help. Bottom line here truly worth keeping a food diary to see how much calcium your diet is giving you. Interestingly, the women taking 340 mg/d had comparable or better results than the woman taking 680mg/d an outcome the researchers thought might have been due to the fact that the women taking 340 mg/d took their strontium at night (when bone remodeling is more active), while the woman taking 680 mg/d took her strontium supplement during the day. Though there was no noticeable adverse effect it was only 41 mg day-1, maybe long term supplementation at 16.6 times that much could pose an issue. I just want to give an enormous thumbs up for the great info youve here on this post. I suggest you ask your doctor about getting a Vertebral Deformity Assessment this is done on DEXA machines using special software that takes a side (lateral) view of the spine and provides an image of each vertebra to see if there are any deformities or fractures. Ammann P, Shen V, Robin B, Mauras Y, Bonjour JP, Rizzoli R. Service of Bone Diseases, World Health Organization Collaborating Center for Osteoporosis Prevention, Geneva 14 CH-1211, Switzerland. Within 10 months of using AlgaeCal Plus, my 2012 DXA showed BMD 3.2% in my hip, and 6% in my spine from 2011. In brief, check this persons credentials (where did this man get his medical training? I recently had a DEXA scan which showed some improvement in my bone density. I have two questions..one regarding your recommended daily dosage for strontium and the second regarding your recommended daily dosage for Vitamin K4. Do you have any information regarding this product? postmenopausal vertebral osteoporosisa 2-year randomized placebo controlled And this applies to ANYTHING you see on the web. I have discussed all of the nutrients bone requires and how to determine how much you need of each in Your Bones. For example, I personally need 10,000IU of D3/day to get my blood levels into good range, so I need at least 300 mcg of MK-7. When I started him on this protocol about a year ago now, he was limping, wearing a knee brace, and fearing his bball playing days were over. My question is, are there any negative side effects of taking the strontium citrate and calcium around the same time? Shouldnt the label reflect the actual percentage? This is why you want to be sure to be consuming twice as much calcium (from diet and supplements combined) as strontium. I did my researched and came across your web and decided to order and which I just received my 3 months supply today. Medications and supplements. Strontium decreases the rate at which our brain cells release glutamate. What you want to do is take your strontium at a time of day when you are NOT consuming any calcium. Re their recommendation of impact exercise for the participants in this study, I believe it was reasonable and helpful here are the reasons why. You should also avoid taking it with calcium supplements or calcium-rich foods or consuming these foods 2 hours prior or 4 hours after taking the medication because the calcium can decrease the body's ability to absorb the hormone. I took it for a few weeks, but didnt realize that I should also have avoided calcium in food when taking the AM packet that contained the Strontium Citrate, so I now realize that I should have avoided eating my cereal and almond milk for breakfast, as it contained calcium. Epub 2016 Oct 21. This individual had results that were slightly under 2,000 ng/ml which, in her assessment, is over 4,000 % higher than the upper normal limit of 45.0 ng/ml. Yes, do have fruits and vegetables daily, flax seed and chia seed (when I remember) and a relatively healthy diet. Dr. Grout does offer BHRT. Be well, The issue is not bone mineral density, but the bodys exposure to estrogens when they are being metabolized into pro-inflammatory, potentially carcinogenic derivatives. My bloodwork is also great! And neither study shows strontium depositing primarily into cortical bone. What is the measurement being used here? The optimal duration of use of Boniva has not been determined. As a result, a treatment with Strontium should not induce any alteration of bone mineral.. Servier now had a patentable, exclusive strontium bone drug which was sold beginning in the early 2000s under the trade name ProtelosTM. If you take l-arginine during the night you will get all of the benefits of Nitric Oxide and anti-aging. In conclusion, SR therapy increased vertebral BMD and reduced the incidence of vertebral fractures. But 3 hours afer eating a bit of yogurt as part of a fruit dessert should not be an issue. I learned so much! Your doctor will be aware of the connection between hypothyroidism and hair loss, but may not be aware that hyperprolactinemia is another potential cause, so Im pasting in a recent citation on this here: Ziai M, Cifuentes L, Grosber M, et al. I have Your Bones on my Kindle now so I am reading (but must admit at my age I do forget rather quickly so sometimes need to re-read..) How did your DEXA tests turn out after being on AlgaeCal? Im leery of the strontium replacing calcium in my bones, where calcium is what is supposed to be forming bones, not strontium. So how can the real amount, if any, of increase in strength and quality of bone be known or determined? As I mentioned, there have been no reports of stomach upset caused by the natural form of strontium, strontium citrate, in any of the studies conducted over the last 100+ years. Not to worry, this can be rectified! I have had 3 allergic reactions to antibiotics, so am careful about what I take. Hi Audrey, trial. I just started taking AlgaeCal Feb. 10th I scrolled on your FB page &a read something about too much Stronium is not good for kidneys? ND? And we can check, in terms of our bones, whats happening with NTx and DXA tests, also our vitamin D levels, and Im hoping soon the test for vitamin K levels (its called unOC, which stands for uncarboxylated osteocalin) will be widely available. I am glad that AlgaeCal has lots of Vitamin D in it, I completely agree that the D.V of 400 and the DRI of 600 is way too low. I dont mind the small inconvenience because I know I am rebuilding my bones. Your thoughts on this would be most appreciated. My results have convinced me that AlgaeCal is the calcium supplement I am going to continue to use. Thanks! In contrast, the MK-7 form remains bioactive in the body for about 3 days this is one of the key reasons why you need so much less just 120 mcg has been shown in the research to be effective for MOST people. Very glad to hear you are doing many of the things I noted that are essential for healthy bones. You will not need your former calcium supplement. Youre on your way back to healthy bones! Lastly, re bio-identical hormone replacement. Strontium Boost is safe for adults of all ages! Taking 1 capsule several times a day will be a bit of a hassle as you must take strontium several hours before or after consuming calcium, so it would be easier to take 2-3 at once. If I have strontium two hours before the kale will that be sufficient? Aquamin has no valid studies on bone health. Problems were minor and did not prevent any of the women from continuing to exercise although for a few of these women, their program were modified to meet the individuals needs. Or does it have something to do with calculated equivalences? Radioactive strontium isotopes (85Sr and 89 Sr) are also used as delivery agents for chemotherapy drugs and for diagnostic purposes in kinetic studies. If so, what product and at what dosage? No adverse effects. I dont want to do something that would cause other problems. In other words, your DXA BMD score is, in fact, an estimate its a very good estimate, but it is not 100% an accurate number in the way you are using this adjective. I always thought it just added to the calcium and helped strengthen. Vitamin K2 is fat-soluble its in the fat, so when the fat is removed, so is the K2. ( I hope you are eating lots of these vegetables like spinach, kale, Swiss chard, broccoli because they contain not only calcium but other minerals and vitamins essential for building healthy bones (e.g., vitamin K1, magnesium, boron). Hi Lara, My kidneys are getting old. NO adverse side effects. Thrilled to have found this which appears to be so promising. Pilates exercises with an instructor who has been trained to work specifically with people with bone loss may be very helpful for you. The aim of the strontium ranelate (SR) for treatment of osteoporosis (STRATOS) trial was to investigate the efficacy and safety of different doses of SR, a novel agent in the treatment of postmenopausal osteoporosis. That said, with your levels being in the 80s, the full dose of Strontium Boost should be just fine, however we would still recommend checking this over with your doctor, and continue to monitor these levels for any changes. Thanks Lara. While the baseline levels of 0.38 0.05 and 0.39 0.10 for the finger and ankle, respectively, were on par with those previously reported in Caucasians among twenty-two healthy non-supplementing strontium individuals by our group, an increase began to be seen after 24 hrs of 0.62 0.14 and 0.45 0.12 for the finger and ankle, respectively. You can, of course, purchase boron separately (and have to open yet another bottle and take yet another pill every day), but I, personally, just rely on AlgaeCal Plus, which contains not only the calcium our bones require, but also the 3 milligrams of boron, plus magnesium and vitamin D3. Whether this animal study even relates to us humans is highly questionable. In order to not loose more bone, I decided to also take StrontiumBoost, which I just ordered. Since a significant amount of other research over the last 40 years has never shown any adverse effects from strontium combined with natural salts, like citrate (unless way more strontium was being consumed than calcium and then the adverse effect was rickets, not VTE or DRESS syndrome), it is only rational to conclude that the cause of the ADRs is the new-to-nature ranelic acid (ranelate in the combo). And ever since being off it, I dont feel it hardly anymore Im just a product user, consumer, , with osteopenia and prone to research things . This woman does better with MK-4. 2012 Oct;33(10):1277-84. doi: 10.1038/aps.2012.83. As you know, our bones continue to remodel throughout our lives, so the therapies used to support healthy bones must be ones we can rely on long-term. this does not seem like it honors the natural biological process of building bone structure. https://www.progressivenutritional.com/products/multivitamin-for-women-50. 2011 Oct;89(4):295-302.PMID: 21789637) The only potential issue here is that DHEA is an androgen and a precursor to testosterone, so taking too much DHEA (for YOU) can cause the appearance of secondary male sexual characteristics in women e.g., acne, growth of excess body and facial hair, loss of scalp hair. Her BMD has continually increased, and after 800 days (the most recent check before the paper was submitted to Bone) strontium retention at her finger and ankle were 7 and 15 times higher than the initial baseline reading. 2002-2023 AlgaeCal. I shall be coming back to your blog soon. Once improvement has been made then dropping down to a lower dose, say half to one-quarter this amount, may be sufficient. This is because food and some drinks can affect the way these medicines work. Because I am 65yrs. Therapeutically, radioactive strontium is used to treat metastatic cancer but can damage bone marrow and act as a potential carcinogen itself at high doses. Yes, you can take Strontium and Magnesium at the same time. I ordered the AlgeaCal plus and the Strontium can I just take the calcium without the other and still see results with diet and exercise (elliptical 3 xs a week , kettlebell 3 xs a week and yoga 2 xs per week? Outside of 2 studies conducted more than 50 years ago in which WAY more strontium was consumed along with virtually no calcium and ricket-like bone malformations occurred, the only adverse health effects noted in the peer reviewed medical literature with strontium are seen the patented drug version, strontium ranelate, which significantly increases risk for VTE and DRESS syndrome plus a number of other unpleasant but less deadly effects. The small amount of estrogen produced in our bones, blood vessels and brain is extremely important for our health. My DEXA results were excellent, showing bones in the healthy, normal range, where they have remained, which I credit in large part to taking AlgaeCal Plus, Strontium Boost and, since it became available, Triple Power Omega 3 Fish Oil. Creatinine is a breakdown product of creatine phosphate in muscle; its usually produced at a fairly constant rate by the body and is eliminated in urine. Is she taking this anticoagulant? 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